Table 2.
Effect of yohimbine, ondansetron, L-NAME, glibenclamide and ruthenium red against MO-induced visceral pain in mice
| Group | Dose (mg/kg) | Specific behaviors |
|---|---|---|
| Normal |
- |
18.14 ± 3.44* |
| Vehicle |
- |
44.17 ± 5.59 |
| Yohimbine |
2 |
22.28 ± 3.53* |
| Ondansetron |
0.5 |
44.75 ± 5.89 |
| L-NAME |
20 |
27.13 ± 3.74 |
| Glibenclamide |
5 |
40.88 ± 8.39 |
| Ruthenium red | 0.3 | 29.25 ± 4.98 |
Values represent the mean ± SEM of pain-related behaviors (licking of abdomen, stretching, abdominal retractions). *p < 0.05 versus vehicle (ANOVA, Student-Newman-Keul’s test).