Table 1. Factors associated with treatment completion.
Factor | Level | n | % | n who completed treatment | % completed treatment | Odds Ratio (95% CI) univariate | P value | Odds Ratio (95%CI) multivariate | P value |
Sex | Female | 123 | 57% | 93 | 76% | 1.0 (0.5 to 1.9) | 0.95 | 1.1 (0.6 to 2.2) | |
Male | 93 | 43% | 70 | 75% | 1.0 | 1.0 | 0.7 | ||
Age | 0–14 years | 51 | 24% | 41 | 80% | 1.8 (0.8 to 4.0) | 1.3 (0.5 to 3.3) | ||
≥35 years | 56 | 26% | 46 | 82% | 2.0 (0.9 to 4.4) | 1.2 (0.4 to 3.5) | |||
15–34 years | 109 | 50% | 76 | 70% | 1.0 | 0.1 | 1.0 | 0.9 | |
Country of birth | Overseas born, immigration<2 years ago | 19 | 9% | 15 | 79% | 1.2 (0.4 to 3.9) | 0.8 (0.2 to 3.4) | ||
Overseas born, immigration 5–10 years ago | 38 | 18% | 28 | 74% | 0.9 (0.4 to 2.1) | 0.7 (0.2 ton 1.9) | |||
Overseas born, immigration ≥10 years ago | 69 | 32% | 51 | 74% | 0.9 (0.4 to 1.8) | 0.6 (0.2 to 1.5) | |||
Overseas born, no info on date of immigration | 2 | 1% | 2 | 100% | not estimable | not estimable | |||
Australian born | 88 | 41% | 67 | 76% | 1.0 | 0.99 | 1.0 | 0.8 | |
Health care workera) | Yes | 21 | 10% | 16 | 76% | 1.0 (0.4 to 3.0) | 1.2 (0.3 to 4.6) | ||
No | 195 | 90% | 147 | 75% | 1.0 | 0.9 | 1.0 | 0.8 | |
TST conversionb) | yes | 58 | 27% | 41 | 71% | 0.7 (0.4 to 1.4) | 0.8 (0.4 to 1.8) | ||
no | 158 | 73% | 122 | 77% | 1.0 | 0.3 | 1.0 | 0.6 | |
CXR | abnormal | 17 | 8% | 16 | 94% | 5.7 (0.7 to 44.3) | 6.1 (0.7 to 51.2) | ||
Missing info | 2 | 1% | 2 | 100% | not estimable | not estimable | |||
normal | 197 | 91% | 145 | 74% | 1.0 | 0.2 | 1.0 | 0.3 | |
Reason for treatment for LTBI | TB household contact | 92 | 43% | 70 | 76% | 1.0 | 0.1 | 1.0 | 0.2 |
TB non-household contact | 57 | 26% | 37 | 65% | 0.6 (0.3 to 1.2) | 0.5 (0.2 to 1.2) | |||
immunosuppression | 47 | 22% | 34 | 85% | 1.8 (0.7 to 4.6) | 1.9 (0.6 to 6.4) | |||
other | 20 | 9 | 1.3 (0.4 to 4.2) | 1.0 (0.2 to 4.9) | |||||
Patient's language of communication | Other than English | 23 | 11% | 17 | 74% | 0.9 (0.3 to 2.5) | 0.8 (0.2 to 2.8) | ||
Missing info | 3 | 1% | 3 | 100% | not estimable | not estimable | |||
English | 190 | 88% | 143 | 75% | 1.0 | 0.99 | 1.0 | 0.9 | |
Employment status | Unemployed | 8 | 4% | 7 | 88% | 1.3 (0.7 to 2.5) | 2.0 (0.2 to 18.6) | ||
missing info | 9 | 4% | 6 | 67% | 0.7 (0.2 to 3.0) | 0.5 (0.1 to 2.7) | |||
employed or child or student or other | 199 | 92% | 150 | 75% | 1.0 | 0.6 | 1.0 | 0.6 |
a) Includes all health care workers not just those who received LTBI treatment as a consequence of routine health care worker screening
b) TST conversion defined as an initial TST ≤10 mm with an increase in TST size of ≥6 mm and a TST≥10 mm at follow up
c) Adjusted for all covariates except age and baseline transaminases, as those two variables are likely to be associated with adverse events based on previous clinical experience.