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. 2012 Nov 5;7(11):e48900. doi: 10.1371/journal.pone.0048900

Table 1. Factors associated with treatment completion.

Factor Level n % n who completed treatment % completed treatment Odds Ratio (95% CI) univariate P value Odds Ratio (95%CI) multivariate P value
Sex Female 123 57% 93 76% 1.0 (0.5 to 1.9) 0.95 1.1 (0.6 to 2.2)
Male 93 43% 70 75% 1.0 1.0 0.7
Age 0–14 years 51 24% 41 80% 1.8 (0.8 to 4.0) 1.3 (0.5 to 3.3)
≥35 years 56 26% 46 82% 2.0 (0.9 to 4.4) 1.2 (0.4 to 3.5)
15–34 years 109 50% 76 70% 1.0 0.1 1.0 0.9
Country of birth Overseas born, immigration<2 years ago 19 9% 15 79% 1.2 (0.4 to 3.9) 0.8 (0.2 to 3.4)
Overseas born, immigration 5–10 years ago 38 18% 28 74% 0.9 (0.4 to 2.1) 0.7 (0.2 ton 1.9)
Overseas born, immigration ≥10 years ago 69 32% 51 74% 0.9 (0.4 to 1.8) 0.6 (0.2 to 1.5)
Overseas born, no info on date of immigration 2 1% 2 100% not estimable not estimable
Australian born 88 41% 67 76% 1.0 0.99 1.0 0.8
Health care workera) Yes 21 10% 16 76% 1.0 (0.4 to 3.0) 1.2 (0.3 to 4.6)
No 195 90% 147 75% 1.0 0.9 1.0 0.8
TST conversionb) yes 58 27% 41 71% 0.7 (0.4 to 1.4) 0.8 (0.4 to 1.8)
no 158 73% 122 77% 1.0 0.3 1.0 0.6
CXR abnormal 17 8% 16 94% 5.7 (0.7 to 44.3) 6.1 (0.7 to 51.2)
Missing info 2 1% 2 100% not estimable not estimable
normal 197 91% 145 74% 1.0 0.2 1.0 0.3
Reason for treatment for LTBI TB household contact 92 43% 70 76% 1.0 0.1 1.0 0.2
TB non-household contact 57 26% 37 65% 0.6 (0.3 to 1.2) 0.5 (0.2 to 1.2)
immunosuppression 47 22% 34 85% 1.8 (0.7 to 4.6) 1.9 (0.6 to 6.4)
other 20 9 1.3 (0.4 to 4.2) 1.0 (0.2 to 4.9)
Patient's language of communication Other than English 23 11% 17 74% 0.9 (0.3 to 2.5) 0.8 (0.2 to 2.8)
Missing info 3 1% 3 100% not estimable not estimable
English 190 88% 143 75% 1.0 0.99 1.0 0.9
Employment status Unemployed 8 4% 7 88% 1.3 (0.7 to 2.5) 2.0 (0.2 to 18.6)
missing info 9 4% 6 67% 0.7 (0.2 to 3.0) 0.5 (0.1 to 2.7)
employed or child or student or other 199 92% 150 75% 1.0 0.6 1.0 0.6

a) Includes all health care workers not just those who received LTBI treatment as a consequence of routine health care worker screening

b) TST conversion defined as an initial TST ≤10 mm with an increase in TST size of ≥6 mm and a TST≥10 mm at follow up

c) Adjusted for all covariates except age and baseline transaminases, as those two variables are likely to be associated with adverse events based on previous clinical experience.