Table 4.
Results of multivariate aalysis
|
Variable |
Hazard ratio |
95% confidence interval |
Pvalue* |
|
|---|---|---|---|---|
| Lower | Upper | |||
|
Using each RAR | ||||
| Age |
1.01 |
0.41 |
2.48 |
0.986 |
| Stage |
3.54 |
1.01 |
12.39 |
0.048 |
| ER |
1.63 |
0.61 |
4.34 |
0.325 |
| PR |
0.82 |
0.32 |
2.13 |
0.690 |
| HER2 |
0.48 |
0.19 |
1.17 |
0.105 |
| RAR-G12 |
2.55 |
0.73 |
8.90 |
0.141 |
| RAR-G13 |
5.36 |
1.80 |
15.98 |
0.003 |
|
Using RAR double-positives | ||||
| Age |
1.00 |
0.41 |
2.44 |
0.993 |
| Stage |
3.73 |
1.06 |
13.04 |
0.040 |
| ER |
1.60 |
0.61 |
4.24 |
0.343 |
| PR |
0.84 |
0.32 |
2.15 |
0.709 |
| HER2 |
0.46 |
0.19 |
1.14 |
0.094 |
| RAR-G12*RAR-G13 | 7.31 | 2.65 | 20.15 | 0.0001 |
RAR-G12*RAR-G13: NUPR1 (RAR-G12) and ERBB2 (RAR-G13) copy number gain double-positives.
*Significant result (P < 0.05).