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. 2012 Aug 10;2(5):606–619. doi: 10.1002/brb3.81

Table 5.

Areas showing positive correlations between scales measuring symptom severity in the ASD group and increased activity when viewing “beat gesture with speech” versus “still frame with speech”

Anatomical region Peak (MNI; mm) Extent (voxels) Max (t) Cluster (P)
ADOS-G Communication Subscale
 Left inferior and middle occipital gyri and posterior middle temporal gyrus −34 −68 0 800 10.03 0.001
 Right posterior inferior and middle temporal gyri, inferior and middle occipital gyri and calcarine and lingual gyri 50 −72 0 725 24.92 0.001
 Right hippocampus 22 −28 −4 57 6.14 0.034
ADOS-G Social Subscale
 Left inferior and middle occipital gyri and posterior middle temporal gyrus −34 −66 −2 961 9.86 0.001
 Right posterior inferior and middle temporal gyri, inferior and middle occipital gyri and calcarine and lingual gyri 50 −68 2 782 20.21 0.001
 Right hippocampus 22 −28 −4 91 6.17 0.002
Social Responsiveness Scale (SRS)
 Left inferior and middle occipital gyri and posterior middle temporal gyrus −34 −66 −2 822 8.07 0.001
 Right posterior inferior temporal gyrus and inferior and middle occipital gyri and lingual gyrus 50 −72 0 701 23.61 0.001
 Right hippocampus 22 −28 −4 36 6.13 0.028

ADOS-G, Autism Diagnosis Observation Schedule-Generic (Lord et al. 2000); x, y, and z = the MNI coordinates (mm) corresponding to the left–right, anterior–posterior, and inferior–superior axes, respectively; t, the highest t-score within a region; thresholded at t > 3.36 (P < 0.005); corrected for multiple comparisons at the cluster level (P < 0.05).