Figure 2. CSC treatment induces the expression and membrane localization of ABCG2.
(A) Immunofluorescence microscopy identifies the cellular localization of ABCG2 with and without CSC. Results indicate that CSC exposure induces translocation of ABCG2 to the plasma membrane in 10B and A549. (B) Western blot analysis shows dose dependent increase in ABCG2 expression in response to CSC treatment.