Skip to main content
. 2012 Nov 5;7(11):e47764. doi: 10.1371/journal.pone.0047764

Table 6. Differential biological process associated with BM-MSCs.

Go Term Total genes Q value Representative gene title
Cholesterol biosynthesis 16 0.0 DHCR7, IDI1, FDPS, DHCR24
Fatty acid biosynthesis 10 0.0 PRKAB2,PTGS1, SCD, FASN
Negative regulation of transcription factor activity 5 7.9E-5 ID1, ID3, ID2
Negative regulation of cell proliferation 12 8.5E-5 IL6, MDM2, GPNMB, IL8, EREG
Regulation of transcription, DNA-dependent 62 1.17E-4 BHLHB2, MEOX2, MEOX2, ZNF655
Anti-apoptosis 8 6.23E-4 DDAH2, MALT1, HIPK3, IER3, BNIP2
Complement activation, classical pathway 5 9.76E-4 C1S, SERPING1, C7, CD46
Keratinocyte differentiation 4 0.002 PTGS1, EREG, PTGS2
Cell-cell signaling 19 0.002 NDP, NAMPT, IL6, LEP, AREG
Negative regulation of cell adhesion 3 0.002 CD164, Q8NFD8_HUMAN, ADAMDEC
Regulation of cyclin-dependent protein kinase activity 4 0.003 CCNA2, CCNE2, CDKN2A, RGC32
Cell division 4 0.004 CAPG, CDC2, CCNB1, CCND2, CCNA2
Cytokinesis 4 0.005 DIAPH2, ANLN, PRC1
Mitosis 11 0.006 PBK, CAPG, CDC2, CCNB1, CCNA2
Chemotaxis 7 0.008 CXCL5, CXCL2, IL8, CXCL6, CXCL1
Positive regulation of mitosis 3 0.008 EREG, NUSAP1
Positive regulation of I-kB kinase/NF-kB cascade 6 0.009 MALT1, CASP1, TNFSF10, TRADD
Regulation of progression through cell cycle 15 0.012 CDC2, CCNB1, MDM2, CCND2, FOSB
TGF-beta receptor signaling pathway 3 0.012 SMAD7, LTBP2, SMAD3
Positive regulation of cell proliferation 8 0.012 NAMPT, IL6, CXCL5, TSHR, TTK
Angiogenesis 5 0.015 IL8, EREG, ANG, ANGL4_HUMAN
Innate immune response 5 0.02 C1S, SERPING1, C7, CD46
Negative regulation of lipoprotein lipase activity 2 0.021 ANGL4_HUMAN
Cytokinesis after mitosis 2 0.021 NUSAP1
Cell cycle checkpoint 3 0.024 RAD1, CCNE2, CDKN2A
Cell cycle arrest 4 0.024 DHCR24, IL8, CDKN2A, Q8N9B5
Protein ubiquitination 3 0.032 MYLIP, MDM2, FBXO9
Negative regulation of transcription 3 0.032 NAB1, EREG, ID1, ID4, ID3