Table 1. Receptor expression levels and ligand binding affinities of the hKOR-WT and hKOR-10KR.
[3H]diprenorphine | U50,488H | Dyn A | ||
---|---|---|---|---|
|
||||
Bmax (pmol/mg protein) | Kd (nM) | Ki (nM) | Ki (nM) | |
hKOR-WT | 1.71 ± 0.17 | 0.12 ± 0.01 | 1.45 ± 0.14 | 0.10 ± 0.01 |
| ||||
HKOR-10KR | 2.20 ± 0.17 | 0.14 ± 0.02 | 1.64 ± 0.26 | 0.11 ± 0.02 |