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. Author manuscript; available in PMC: 2013 Nov 5.
Published in final edited form as: Mol Pharm. 2012 Oct 3;9(11):3266–3276. doi: 10.1021/mp300326z

Table 1.

Intrinsic Second Order Hydrolysis Rate Constants for a Related Series of Simple Vinyl Ethers.

Vinyl Ethers kH (M−1s−1) Relative Rates
graphic file with name nihms-412494-t0010.jpg 0.760a 1
graphic file with name nihms-412494-t0011.jpg 53.3b 70.1
graphic file with name nihms-412494-t0012.jpg 276c 363
graphic file with name nihms-412494-t0013.jpg 720000d 947000
graphic file with name nihms-412494-t0014.jpg 0.0000094e 0.0000124
graphic file with name nihms-412494-t0015.jpg 0.255a 0.336
graphic file with name nihms-412494-t0016.jpg 0.072a 0.0947
graphic file with name nihms-412494-t0017.jpg 0. 00267f 0.00351
b

Chiang et al. (1978);

f

Chiang et al. (1978).