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Calculated Proton Affinities and Measured Intrinsic Second Order Rate Constants for mPEG-VE-DOG Lipids with Varying Electronic Properties
| mPEG- VE-Lipid |
Proton Affinity (kcal/mol) |
Second Order Rate Constant (M−1 sec−1) |
|---|---|---|
| ST912 | −240.26 | 5.2 × 104 |
| ST502 | −237.32 | 730 |
| ST505 | “ | 240 |
| ST302 | −215.88 | 1.4 × 10−2 |
| ST305 | “ | 8.3 × 10−3 |
| ST152 | −207.51 | 5 × 10−6 |
| ST155 | “ | 2.5 × 10−5 |
