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. Author manuscript; available in PMC: 2013 Nov 15.
Published in final edited form as: J Immunol. 2012 Oct 3;189(10):5047–5056. doi: 10.4049/jimmunol.1200290

Figure 4. Peptide p9 attenuates I/R-induced injury in a therapeutic and dose dependent manner.

Figure 4

C57Bl/6 mice were subjected to Sham or I/R with or without injection of 40 μM p9 peptides, either prior to ischemia or 5, 15 or 30 min post ischemia (A–B). Additional mice were subjected to Sham or I/R with or without injection of 4–40 μM p9 peptide (C–D). Mid-jejunal sections from appropriately treated C57Bl/6 mice were scored for injury (A, C) and the villus height/crypt depth ratio determined (B, D). * = p ≤ 0.05 compared to Sham + peptide, Φ = p ≤ 0.05 compared to I/R treatment animals not receiving peptides. Each symbol in A and C represents an individual animal. Each bar (B–D) is representative of 4–10 animals and each treatment was performed on at least 2 separate days.