. Author manuscript; available in PMC: 2013 Nov 15.

Published in final edited form as: Toxicol Appl Pharmacol. 2012 Sep 19;265(1):27–42. doi: 10.1016/j.taap.2012.09.008

Table 4.

Genes that were up- or down-regulated in hAT2 cells by the HSulf-1/cadmium combination, normalized to lacZ/cadmium results

Gene	Description	Fold change	Function
BAG3	Bcl-2-associated athanogene 3	−2.0	Anti-apoptosis
HRK	Activator of apoptosis harakiri	−4.0	Pro-apoptosis
TNFRSF9	TNF receptor superfamily member 9	6.7	Pro-apoptosis
CD70	TNF superfamily member 7	5.3	Pro-proliferation

hAT2 cells were transduced for lacZ or HSulf-1 over-expression and treated with or without cadmium. Total mRNA of duplicate samples was isolated, Apoptosis PCR arrays were performed, and results were combined to analyze gene expression. Genes that were up- or down-regulated more than 2-fold over “lacZ/cadmium” levels are indicated. Red, up-regulation; Blue, down-regulation.