Table 1.
Relative cost | Coding variant coverage | Regulatory variant coverage | |
---|---|---|---|
Original GWA array | + | + | + |
Denser GWA arrays | + | ++ | ++ |
IBC array | − | selected | selected |
Metabochip/Immunochip | − | selected | selected |
Exome chip | − | ++ | − |
Imputation of untyped variants | − | ++ | ++ |
Exome sequencing | ++ | +++ | − |
Low read depth genome sequencing | ++ | ++ | ++ |
High read depth genome sequencing | +++ | +++ | +++ |
Symbols indicate lower to higher cost and lower to better coverage: −, +, ++, +++.