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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Curr Diab Rep. 2012 Dec;12(6):643–650. doi: 10.1007/s11892-012-0321-4

Table 1.

Characteristics of genotyping and sequencing technologies

Relative cost Coding variant coverage Regulatory variant coverage
Original GWA array + + +
Denser GWA arrays + ++ ++
 IBC array selected selected
 Metabochip/Immunochip selected selected
 Exome chip ++
Imputation of untyped variants ++ ++
Exome sequencing ++ +++
Low read depth genome sequencing ++ ++ ++
High read depth genome sequencing +++ +++ +++

Symbols indicate lower to higher cost and lower to better coverage: −, +, ++, +++.