Table 2.
Anesthesia | rCBF (% of baseline) | Reperfusion (% of baseline) | Flow transients
|
Infarct size (mm3)
|
Edema % | |||
---|---|---|---|---|---|---|---|---|
Number of PIFTs | Amplitude (% of baseline) | BG | Cortex | Total | ||||
|
|
|
|
|
||||
ISO (ci) (n=25) |
35±12 | 134±53 | 6.1±2.5 | 14±9.7 | 57±10 | 129±25 | 186±29 | 109±5 |
ISO (no) (n=7) |
47±16 | 87±30* | 3.3±1.7** | 19±7.9 | 44±19* | 8±8** | 52±24** | 100±1** |
HALO (ci) (n=14) |
40±13 | 131±31 | 7.4±3.8 | 14±7.7 | 58±10 | 137±37 | 195±39 | 110±6 |
HALO (no) (n=9) |
45±13 | 103±25* | 3.8±1.4** | 18±3.6 | 38±15** | 13±12** | 51±16** | 102±3** |
ISO=isoflurane, HALO=halothane, ci=substantial cortical infarct, no=small or negligible cortical infarct, BG=basal ganglia.
= Significant difference (p<0.05) between the “ci” and “no” subgroup in the same anesthetic groups.
= Significant difference (p<0.01) between the “ci” and “no” subgroup in the same anesthetic groups. Data expressed as mean± SD