Table 3.
Anesthesia | Flow parameters | Range | Discrimination point | Lower border | Upper border | Ratio of CPA to total number |
---|---|---|---|---|---|---|
ISO | CBF % | 9–74 | 62 | 12 | 112 | 26/32 |
No. of PIFTs | 1–12 | 2.8 | −1.2 | 6.8 | 27/32 | |
Reperfusion % | 65–302 | 75 | 6 | 144 | 26/32 | |
Amplitude % | 4–39 | 41 | −15 | 98 | 25/32 | |
| ||||||
HALO | CBF % | 17–76 | 56 | −36 | 149 | 14/23 |
No. of PIFTs | 2–10 | 5.1 | 2.6 | 7.6 | 20/23 | |
Reperfusion % | 67–196 | 103 | 21 | 186 | 17/23 | |
Amplitude % | 5–37 | 20 | −9 | 49 | 15/23 | |
| ||||||
ISO+HALO | CBF % | 9–76 | 59 | 0 | 118 | 41/55 |
No. of PIFTs | 1–12 | 3.8 | 0.2 | 7.4 | 45/55 | |
Reperfusion % | 65–302 | 85 | −1 | 171 | 41/55 | |
Amplitude % | 4–39 | 31 | −18 | 80 | 36/55 |
Discrimination point distinguishes between animals with and without severe cortical infarct. Borders are parameter values beyond which the model would predict an animal with at least 95% certainty. CBF, amplitude and reperfusion are expressed as percent of pre-ischemic baseline. CPA=correctly predicted animals.