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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Exp Gerontol. 2012 Sep 7;47(12):958–965. doi: 10.1016/j.exger.2012.08.013

Figure 5. Cytokine and chemokine analysis in the lungs of uninfected and infected mice.

Figure 5

Basal and post-infection acute cytokine and chemokine profile in lungs from aged (24 month) C57BL/6 mice that had been fed rapamycin short-term (ST-eRapa: basal n=5, acute n=8), long-term (LT-eRapa: basal n=5, acute n=5), or the Eudragit (Control: basal n=3, acute n=6) diet. Mice were challenged intratracheally with 1.0 × 103 cfu of S. pneumoniae serotype 4 strain TIGR4, lungs were collected and homogenized for cytokine/chemokine analysis. Statistical analysis was performed using a one-way ANOVA comparing the rapamycin fed groups versus the control diet. Asterisk denotes a statistically significant difference (P<0.05).