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. Author manuscript; available in PMC: 2013 Nov 15.
Published in final edited form as: J Immunol. 2012 Oct 5;189(10):4787–4796. doi: 10.4049/jimmunol.1200579

Figure 2. SAP is required for the development of pre-activated phenotype in M3-restricted T cells in an IL-4 independent manner.

Figure 2

M3/LemA specific CD8+ T cells were isolated from the spleens of B6, SAP−/− and IL-4−/− mice via tetramer enrichment and analyzed by FACS. (A) Bars represent the number of M3/LemA specific CD8+ T cells per spleen of naïve B6 (n=11), SAP−/− (n=5) and IL-4−/− (n=3) mice, respectively. (B) Histograms represent surface activation marker expression of M3/LemA specific CD8+ T cells isolated from spleens of indicated mice. Data are representative of at least three independent experiments.