Immunolabeling for mGluR4 at the electron microscopic level in the monkey putamen. A) An unlabeled terminal arising from a labeled axon and forming a symmetric synapse on a dendrite. B) A labeled terminal forming a symmetric synapse on a spine. C) A labeled and an unlabeled terminal forming asymmetric synapses on spines. D) A labeled dendrite and a labeled terminal forming a symmetric synapse on a dendrite. E) Histogram showing the breakdown of the proportions of each type of labeled element found in the putamen of normal and MPTP-treated monkeys. n=3 normal, 3 MPTP-treated monkeys. Error bars represent SEM. No significant difference was found between normal and MPTP-treated monkeys. Synapses are identified with arrowheads. Immunoperoxidase labeling is identified with arrows. a – labeled axon, d – labeled dendrite, s - spine, Te – labeled terminal, u.Te – unlabeled terminal.