Table 2.
Gene | Alleles | Explanatory variablesa |
||
---|---|---|---|---|
Color | Geographical region | Color: geographical region | ||
CYP2C8 | *2, *3, *4 | <0.0001 | 0.71 | 0.04 |
CYP2C9 | *2, *3, *5, *11 | <0.0001 | 0.23 | 0.01 |
CYP2C19 | *2, *3, *17 | 0.60 | 0.11 | 0.33 |
ABCB1 | haplotypesb | <0.001 | 0.001 | 0.013 |
SLCO1B1 | haplotypesc | <0.001 | 0.001 | 0.003 |
VKORC1 | 3673A allele | 0.0004 | 0.07 | 0.11 |
3673A genotype | 0.002 | 0.18 | 0.19 |
ap values associated to the “main effects” (Color and geographical region) and their “interaction.”
bHaplotypes comprising the 1236C > T, 2677G > nonG, and 3435C > T loci.
cHaplotypes comprising the 388A > G, 463C > A, and 521T > C loci.