Table II.
Specimen | A | Gl | G | pT | M | Caspase-3
|
Caspase-6
|
Caspase-1
|
Caspase-9
|
Bcl-2
|
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Uncleaved
|
Cleaved
|
Uncleaved
|
Cleaved
|
||||||||||||||||
BPE | PCa | BPE | PCa | BPE | PCa | BPE | PCa | BPE PCa BPE | PCa | BPE | PCa | ||||||||
1 | 62 | 3+4=7 | 3a | 2b | 0 | 3 | 3 | 3 | 1 | 3 | 3 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 |
2 | 52 | 3+3=6 | 2a | 2b | 0 | 2 | 2 | 3 | 1 | 3 | 3 | 2 | 1 | 1 | 1 | 1 | 1 | 3 | 1 |
3 | 63 | 2+3=5 | 1b | 2b | 0 | 2 | 2 | 3 | 2 | 3 | 3 | 2 | 1 | 1 | 1 | 1 | 1 | 3 | 1 |
4 | 62 | 2+3=5 | 2a | 3a | 0 | 2 | 1 | 3 | 3 | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 |
5 | 70 | 3+4=7 | 3a | 2c | 1 | 3 | 1 | 3 | 1 | 3 | 3 | 3 | 1 | 1 | 1 | 2 | 1 | 3 | 1 |
6 | 62 | 3+4=7 | 3a | 2c | 0 | 1 | 2 | 3 | 1 | 3 | 3 | 2 | 2 | 1 | 1 | 1 | 1 | 3 | 1 |
7 | 71 | 3+4=7 | 3a | 3c | 0 | 2 | 3 | 3 | 2 | 3 | 3 | 1 | 1 | 1 | 1 | 1 | 2 | 3 | 2 |
8 | 68 | 2+2=4 | 1b | 2c | 0 | 2 | 1 | 3 | 1 | 3 | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 1 |
9 | 67 | 2+2=4 | 1b | 2a | 0 | 2 | 2 | 3 | 1 | 3 | 3 | 3 | 1 | 1 | 1 | 1 | 1 | 2 | 1 |
10 | 68 | 2+3=5 | 3a | 2c | 0 | 2 | 2 | 2 | 2 | 3 | 3 | 2 | 1 | 1 | 1 | 1 | 1 | 3 | 2 |
11 | 59 | 1+2=3 | 1b | 2b | 0 | 2 | 2 | 3 | 1 | 3 | 2 | 3 | 2 | 1 | 1 | 1 | 1 | 3 | 2 |
12 | 60 | 2+3=5 | 1b | 2b | 0 | 3 | 2 | 3 | 2 | 3 | 3 | 2 | 1 | 1 | 1 | 1 | 1 | 3 | 1 |
13 | 68 | 3+4=7 | 3a | 2c | 0 | 2 | 3 | 2 | 1 | 3 | 3 | 2 | 1 | 1 | 1 | 1 | 1 | 3 | 1 |
14 | 66 | 2+3=5 | 2b | 2a | 0 | 2 | 3 | 2 | 1 | 3 | 2 | 3 | 1 | 1 | 2 | 1 | 1 | 3 | 1 |
15 | 70 | 2+3=5 | 2b | 2b | 0 | 3 | 2 | 3 | 1 | 2 | 3 | 1 | 1 | 2 | 2 | 1 | 1 | 3 | 1 |
16 | 65 | 2+3=5 | 2b | 2a | 0 | 2 | 2 | 3 | 3 | 3 | 3 | 2 | 1 | 2 | 2 | 1 | 1 | 3 | 2 |
17 | 66 | 3+4=7 | 3a | 3a | 0 | 3 | 2 | 3 | 1 | 3 | 3 | 2 | 1 | 1 | 1 | 1 | 2 | 2 | 2 |
18 | 65 | 3+5=8 | 3a | 2b | 0 | 3 | 3 | 3 | 1 | 2 | 3 | 1 | 2 | 1 | 1 | 1 | 1 | 3 | 2 |
19 | 64 | 1+2=3 | 1b | 2a | 0 | * | * | * | * | * | * | * | * | 1 | 1 | 2 | 1 | 2 | 1 |
20 | 65 | 2+3=5 | 2a | 2b | 0 | * | * | * | * | * | * | * | * | 1 | 1 | 1 | 1 | 3 | 1 |
A, age at diagnosis (years); Gl, Gleason score; G, grading; pT, tumour stage; M, metastasis; BPE, benign prostate epithelium, PCa, prostate cancer. Immunohistochemical score: +, 1; ++, 2; +++, 3.
Not investigated due to limited material.