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. 2012 Aug 27;21(23):5131–5146. doi: 10.1093/hmg/dds360

Figure 13.

Figure 13.

ATP production in cerebral cortical tissues from 6-, 12- and 24-month-old APP mice and age-matched non-transgenic WT mice. Significantly decreased ATP production was found in the cerebral cortex from the 6-month-old (P = 0.01), 12-month-old (P = 0.003) and 24-month-old (P = 0.01) APP mice, compared with the 12- and 24-month-old non-transgenic WT mice. Significantly reduced ATP production was found in the 12-month-old (P = 0.01) and 24-month-old (P = 0.01) APP mice, compared with the 6-month-old APP mice.