Table 1.
Correlation between protein network structure and miRNA activity
| Protein connectivity | Clustering coefficient | |
|---|---|---|
| |
R2 (p-value) |
R2 (p-value) |
| FPI-TargetScan |
0.73 (0.004) |
-0.77 (0.01) |
| HPRD-TargetScan |
0.85 (0.001) |
-0.28 (0.2) |
| FPI-miRecord |
0.80 (0.002) |
-0.148(0.8) |
| HPRD-miRecord |
0.64 (0.009) |
-0.537(0.02) |
| Random | -0.26 (0.54) | 0.22 (0.5) |
Spearman’s rank correlation of protein connectivity and clustering coefficient vs. number of targeting miRNAs, significance of correlation is indicated by p-value in brackets, FDR < 0.005.