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Total and antigen-specific IgE in plasma of IL7R−/− and L-sel−/− mice. Following peanut sensitization and challenge, blood levels of total IgE (A, B) and IgE-mediated CPE binding (C, D) were assayed at the 40 minute endpoint. (IL7R−/−n = 3 and Ly5.1 n = 4, representative of 3 experiments; L-Sel−/−n = 5 and Bl/6 n = 7, representative of 4 experiments; ***represents p < 0.001; Error bars = SEM).
