Table 2.
Univariate regression analysis (95% CI) of lipid and glucose metabolism with potential mediators
| Cholesterol | HDL-C | LDL-C | Log(triglycerides) | Glucose | Log(C-peptide) | Insulin resistance | |
|---|---|---|---|---|---|---|---|
| Age |
0.09 (0.00 – 0.18) ** |
0.10 (0.06 – 0.13) **** |
0.14 (0.06 – 0.22) |
0.01 (−0.01 – 0.04) |
0.14 (0.08 – 0.21) **** |
−0.10 (−0.12 - -0.09) **** |
−0.15 (−0.19 - - 0.10) **** |
| Sex (reference: boys) |
0.19 (0.12 – 0.26) **** |
−0.02 (−0.05 – 0.01) |
0.24 (0.17 – 0.30) **** |
0.06 (0.04 – 0.08) **** |
−0.13 (−0.18 - -0.08) **** |
0.02 (0.01 – 0.03) *** |
0.01 (−0.02 – 0.05) |
| Height in meters |
−0.33 (−0.99 – 0.33) * |
0.15 (−0.15 – 0.45) |
−0.03 (−0.66 – 0.60) |
−0.01 (−0.19 – 0.18) |
1.20 (0.73 – 1.68) **** |
−0.13 (−0.25 – -0.00) ** |
−0.07 (−0.37 – 0.22) |
| Size at birth (reference: AGA) |
|
|
|
|
|
|
|
| SGA |
0.06 (−0.11 – 0.22) |
0.08 (0.01 – 0.16) ** |
−0.04 (−0.19 – 0.12) |
0.01 (−0.04 – 0.05) |
−0.02 (−0.14 – 0.10) |
−0.01 (−0.04 – 0.02) |
0.00 (−0.07 – 0.07) |
| LGA |
−0.12 (−0.22 - -0.01) ** |
−0.04 (−0.09 – 0.01) |
−0.10 (−0.20 – 0.00) * |
−0.01 (−0.04 – 0.02) |
0.01 (−0.06 – 0.09) |
0.01 (−0.01 – 0.03) |
0.04 (0.00 – 0.09) * |
| Maternal BMI |
0.00 (−0.01 – 0.01) |
0.00 (−0.01 – 0.00) |
0.01 (−0.00 – 0.02) * |
0.00 (−0.00 – 0.00) |
0.01 (−0.00 – 0.02) |
0.00 (−0.00 – 0.00) |
0.00 (−0.01 – 0.00) |
| Breastfeeding duration (reference: > 3 months) |
|
|
|
|
|
|
|
| < 1 month |
−0.02 (−0.11 – 0.07) |
−0.04 (−0.08 – 0.00) |
0.00 (−0.09 – 0.09) |
0.02 (−0.00 – 0.05) * |
−0.01 (−0.08 – 0.06) |
0.00 (−0.01 – 0.02) |
0.00 (−0.04 – 0.04) |
| 1 – 3 months |
0.08 (−0.01 – 0.17) |
0.01 (−0.03 – 0.05) |
0.07 (−0.02 – 0.15) |
0.00 (−0.02 – 0.03) |
0.00 (−0.06 – 0.07) |
0.00 (−0.02 – 0.01) |
0.01 (−0.03 – 0.05) |
| Childhood sdsBMI |
0.01 (−0.04 – 0.06) |
−0.01 (−0.03 – 0.01) |
0.01 (−0.03 – 0.05) |
0.01 (−0.01 – 0.02) |
0.05 (0.02 – 0.08) *** |
0.03 (0.02 – 0.04) **** |
0.04 (0.02 – 0.06) **** |
| Sports club member (reference: yes) |
−0.01 (−0.09 – 0.07) |
0.01 (−0.03 – 0.04) |
−0.02 (−0.09 – 0.05) |
0.00 (−0.02 – 0.02) |
0.05 (−0.01 – 0.10) * |
−0.01 (−0.02 – 0.01) |
0.00 (−0.03 – 0.04) |
| Walking to school (reference: > 60 min a week) |
|
|
|
|
|
|
|
| No |
0.09 (−0.02 – 0.21) |
−0.02 (−0.07 – 0.03) |
0.04 (−0.07 – 0.15) |
0.00 (−0.03 – 0.03) |
0.01 (−0.07 – 0.09) |
0.01 (−0.01 – 0.04) |
0.03 (−0.02 – 0.08) |
| < 30 min a week |
0.07 (−0.06 – 0.19) |
−0.01 (−0.07 – 0.05) |
0.05 (−0.07 – 0.17) |
0.00 (−0.04 – 0.03) |
0.00 (−0.09 – 0.09) |
0.01 (−0.02 – 0.03) |
0.01 (−0.05 – 0.06) |
| 31 – 60 min a week |
0.05 (−0.08 – 0.18) |
−0.04 (−0.10 – 0.02) |
0.03 (−0.10 – 0.16) |
0.01 (−0.03 – 0.05) |
0.06 (−0.03 – 0.16) |
0.02 (−0.01 – 0.04) |
0.05 (−0.01 – 0.11) |
| Cycling to school (reference: > 60 min a week) |
|
|
|
|
|
|
|
| No |
−0.04 (−0.17 – 0.09) |
−0.05 (−0.10 – 0.01) |
−0.07 (−0.19 – 0.05) |
0.01 (−0.03 – 0.04) |
−0.01 (−0.10 – 0.09) |
0.00 (−0.02 – 0.03) |
−0.02 (−0.07 – 0.04) |
| < 30 min a week |
−0.06 (−0.21 – 0.09) |
−0.03 (−0.10 – 0.04) |
−0.07 (−0.21 – 0.07) |
−0.02 (−0.06 – 0.02) |
0.03 (−0.08 – 0.14) |
0.00 (−0.02 – 0.03) |
−0.02 (−0.09 – 0.05) |
| 31 – 60 min a week | −0.06 (−0.22 – 0.10) | −0.01 (−0.08 – 0.07) | −0.08 (−0.23 – 0.08) | −0.01 (−0.06 – 0.03) | 0.02 (−0.10 – 0.14) | 0.01 (−0.02 – 0.05) | 0.00 (−0.07 – 0.08) |
* p < 0.1; ** p <0.05; *** p < 0.01; ****p < 0.001.