Skip to main content
. 2012 Nov 6;7(11):e48975. doi: 10.1371/journal.pone.0048975

Figure 1. Developmental milestones, brain weight and social recognition in pre-weanling TPH2−/− pups.

Figure 1

(A) acquisition of somatosensory reflexes and developmental milestones from PND 1–19. The indicated reflexes and milestones were considered acquired when they occurred for the second day in a row. (B) brain to body weight ratios in PND 25–28 mice and (C) maternal scent recognition in PND 14 mice. Data in panels (A) and (C) was collected from 6 independent litters for each genotype. Data included in panel (B) was based on results from 18 TPH2−/− (7 male, 11 female) and 31 WT controls (16 male, 15 female). The main effect of sex was not significant so data for males and females is combined. Data are presented as mean ± standard errors of the mean. Symbols indicate significant differences versus WT controls. * p<0.05; ** p<0.01; *** p<0.001.