Figure 5. Repetitive behaviors in TPH2−/− weanling mice.
(A) nestlet shredding based on 18 TPH2−/− mice (10 male, 8 females) and 21 WT controls (12 males, 9 females) , (B) number of marbles buried based on 23 TPH2−/− mice (12 males, 11 females) and 20 WT controls (10 males, 10 females), (C) latency to start digging (left y-axis) based on 20 TPH2−/− mice (10 males, 10 females) and 21 WT controls (11 males, 10 females) and total time spent digging (right y-axis) based on 20 TPH2−/− mice (10 male, 10 female) and 21 WT controls (11 male, 10 female). The main effect of sex was not significant for any test so data for males and females is combined. Data are presented as mean ± standard errors of the mean. Symbols indicate significant differences from WT controls. * p<0.025; *** p<0.001.