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Survival analysis among 376 MS patients (SP + RR; n=103+273) stratified by the HEPC -582AG SNP. The survival trend of the RR status among MS patients was significantly different when stratified by HEPC SNP. The comparison yields an increased chance to progress in the secondary progressive MS course among G-carriers (dashed line) (HR=3.55; 1.83-6.84; log-rank P=0.00006).
