Table 3. Effect of paeonol and danshensu on antioxidant enzymes activity in rats.
Group(s) | SOD | CAT | GPx | GST | GR |
Control | 91.19±3.52 | 87.33±2.70 | 8.65±0.64 | 12.28±0.51 | 11.94±0.67 |
ISO (85 mg/kg, s.c.) | 55.57±3.65* | 45.93±2.19* | 3.82±0.48* | 6.48±0.74* | 6.61±0.67* |
Pae (80 mg/kg, i.g.)+ISO | 75.61±3.54# | 64.15±3.18# | 5.08±0.54 # | 8.02±0.32# | 7.57±0.46& |
DSS (160 mg/kg, i.g.)+ISO | 81.57±3.50 # | 69.54±3.02# | 6.40±0.49# | 9.11±0.33# | 8.45±0.45# |
Pae+DSS+ISO | 88.54±3.53 # @ ¥ | 83.93±3.02# @ $ | 8.04±0.65# @ $ | 11.67±0.41# @ $ | 11.29±0.74# @ $ |
Results are expressed as mean ± S.D. (n = 8).
P<0.001 vs. Control;
P<0.05 vs. ISO,
P<0.001 vs. ISO;
P<0.001 vs. Pae+ISO;
P<0.01 vs. DSS+ISO,
P<0.001 vs. DSS+ISO (one-way ANOVA).
Activity is expressed as units/mg protein for SOD, µmol of H2O2 decomposed/second/mg protein for CAT, µmol of GSH oxidized/min/mg of protein for GPx, µmol of CDNB conjugated/min/mg protein for GST and µmol of GSSG utilized/min/mg protein for GR.