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. 2012 Nov 6;7(11):e47835. doi: 10.1371/journal.pone.0047835

Figure 2. Role of MBL in host resistance to T. cruzi Y strain infection.

Figure 2

WT or MBL−/− mice were infected with trypomastigotes of the reticulotropic, Y strain of T. cruzi and monitored daily for parasitemia and mortality (A). Symbols represent the mean of 10 animals per group. At the indicated time points after infection, levels of parasite DNA in the spleen were quantified by real-time PCR (B). Serum levels of IL-12/23p40 and IFN-γ were determined by ELISA 8 days after infection (C). Each symbol in (B) and (C) corresponds to an individual animal, dashed lines the mean of each group and solid lines the standard error of the mean (SEM). The experiments shown are representative of at least two performed. *, Indicates statistically significant differences between groups.