Table 3. Leisure time physical activity and hazard ratio of mortality and years of life gained after age 40.

Variable	Physical Activity Level (MET-h/wk)
	0	0.1–3.74	3.75–7.4	7.5–14.9	15.0–22.4	22.5+
Number of participants	50,555	112,661	60,132	167,931	118,255	145,293
Number of deaths	9,754	18,352	6,968	20,428	11,814	15,149
Unadjusted HR	1.0	0.71	0.66	0.56	0.49	0.49
95% CI	Ref	0.70, 0.73	0.64, 0.68	0.55, 0.57	0.48, 0.51	0.48, 0.50
Gender-adjusted HR	1.0	0.73	0.67	0.57	0.49	0.48
95% CI	Ref	0.71, 0.75	0.64, 0.69	0.55, 0.58	0.48, 0.51	0.47, 0.50
Gender-, smoking-adjusted HR	1.0	0.77	0.70	0.61	0.54	0.53
95% CI	Ref	0.75, 0.79	0.68, 0.73	0.60, 0.63	0.53, 0.56	0.51, 0.54
Multivariable a HR	1.0	0.81	0.76	0.68	0.61	0.59
95% CI	Ref	0.79, 0.83	0.74, 0.78	0.66, 0.69	0.59, 0.63	0.57, 0.61
Years of life gained	—	1.8	2.5	3.4	4.2	4.5
95% CI	Ref	1.6, 2.0	2.2, 2.7	3.2, 3.6	4.0, 4.5	4.3, 4.7

Years of life expectancy gained after age 40 were derived using direct adjusted survival curves [31],[32] for participants who were 40+y of age at baseline (97.5% of participants).

^aHRs were calculated in models stratified by study that used age as the underlying time scale. Multivariable models were adjusted for gender, alcohol consumption (0, 0.1–14.9, 15.0–29.9, 30.0+ g/d), education (did not complete high school, completed high school, post-high-school training, some college, completed college), marital status (married, divorced, widowed, unmarried), history of heart disease, history of cancer, BMI (<18.5, 18.5–19.9, 20–22.4, 22.5–24.9, 25–27.4, 27.5–29.9, 30+ kg/m²), and smoking status (never, former, current).