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. 2012 Nov 6;7(11):e48539. doi: 10.1371/journal.pone.0048539

Figure 5. Clathrin-regulated endocytosis is a requirement for geldanamycin-stimulated VEGFR2 degradation.

Figure 5

(A) HUVECs subjected to CHC17 knockdown were followed by geldanamycin treatment (4 h) and immunoblot analysis (IB) of indicated proteins. (B) Quantification of mature VEGFR2 levels from the experiments shown in panel A. Error bars denote ±SEM (n≥3), *p<0.05 using one-way ANOVA. CHC17, clathrin heavy chain.