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Abbreviations: CHC17, clathrin heavy chain; E3 ligase, E3 ubiquitin ligase; HSP70, heat shock protein of 70 kDa; HSP90, heat-shock protein of 90 kDa, RNAi, RNA interference; Ub, mono/polyubiquitin modification(s); VEGFR2, vascular endothelial growth factor receptor 2.
