Table 5.
Healing rates according to ulcer size in the duodenal ulcer study
| Ulcer size (mm) | DU |
||||
|---|---|---|---|---|---|
| Eradication therapy + PPI |
Eradication therapy only |
p value | |||
| healed/all patients | % | healed/all patients | % | ||
| ITT analysis | |||||
| 5≤diam<10 | 24(7)/26(7) | 92 [75–99] | 18(3)/21(5) | 86 [64–97] | 0.466 |
| 10≤diam<15 | 8(1)/8(1) | 100 [63–100] | 10(1)/11(1) | 91 [59–100] | 0.381 |
| diam≥15 | 5(3)/6(3) | 83 [36–100] | 5(0)/6(0) | 83 [36–100] | 1.000 |
| PP analysis | |||||
| 5≤diam<10 | 24(7)/24(7) | 100 [86–100] | 18(3)/20(5) | 90 [68–99] | 0.133 |
| 10≤diam<15 | 8(1)/8(1) | 100 [63–100] | 10(1)/10(1) | 100 [69–100] | — |
| diam≥15 | 5(3)/6(3) | 83 [36–100] | 5(0)/5(0) | 100 [48–100] | 0.338 |
Numbers in ( ) denote number of patients in which H. pylori eradication was unsuccessful. Numbers in [ ] are 95%CI: lower to upper. diam: diameter; ITT = intention-to-treat; PP = per protocol. Ratios were analysed using the χ2 test.