Table 1.
5' LTR distribution and methylation analyses near CpG Island associated genes
| DNA methylation analysis | LTR closest to TSS (only full-length copies) | % methylated copies | % methylated copies near CGI promoters |
|---|---|---|---|
| ETn/MusD | 5' LTR (n = 2) | 100 | 100 |
| 3' LTR (n =3) | 33.3 | 0 | |
| IAP | 5' LTR (n = 7) | 100 | 85.7 |
| 3' LTR (n = 12) | 91.6 | 54.5 | |
| Genome-wide analysis | LTR closest to TSS | % LTR associated with CGI promoters | P-value of equality of proportion test |
| IAP (n = 56) | 5' LTR (n = 25) | 80 | 0.03143 |
| 3' LTR (n = 31) | 48 | ||
CGI: CpG Island; ETn/MusD: Early transposon/Mus musculus type D; IAP: Intracisternal (A) Particle; LTR: long terminal repeat; n: number of copies studied; TSS: transcription start site.