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. 2012 Oct 3;13(10):R91. doi: 10.1186/gb-2012-13-10-r91

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Copyright ©2012 Skinner et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Shortest cell processes connection gene sub-networks for genes of selected female ECR chr2-188.8 and male ECR chr1-204.75. (a) ECR chr2-188.8. (b) Male ECR chr1-204.75. Node shapes: oval and circle, protein; diamond, ligand; circle/oval on tripod platform, transcription factor; ice cream cone, receptor; crescent, kinase or protein kinase; irregular polygon, phosphatase. Color code: red, up-regulated genes; blue, down-regulated genes. Arrows with a plus sign indicate positive regulation/activation; arrows with a minus sign indicate negative regulation/inhibition; grey arrows represent regulation; lilac arrows represent expression; purple arrows represent binding; green arrows represent promoter binding; yellow arrows represent protein modification. AA, amino acid; FAS; FGF, fibroblast growth factor; INS, insulin; LRP2, low density lipoprotein receptor-related protein 2; ROS, reactive oxygen species.