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. 2012 Oct 25;8(9):1267–1280. doi: 10.7150/ijbs.4828

Figure 7.

Figure 7

When in the presence of Th17 cells that hyper express IL-17, excessive IL-6 expression induced by a positive feedback loop for IL-6 signaling in non-immune cells plays a role for the development of arthritis in aged F759 mice.