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. 2012 Oct 8;109(43):17543–17548. doi: 10.1073/pnas.1205867109

Fig. 5.

Fig. 5.

Role of hsp90 in antigen sequestration vs. antigen presentation. (A) BMDC cultures were pulsed with OVA for 30 min, followed by a 30-min pulse with 17AAG or dimethyl sulfoxide (as a control) on day 0 (immediately after OVA pulse), or on days 3 and 6 after OVA pulse. All cultures were assayed for B3Z stimulation on day 9 after OVA pulse. (B) BMDC cultures were treated with 17-AAG for 30 min, washed, and placed back in culture. A 30-min pulse of OVA was added on day 3, and the culture was assayed for B3Z stimulation on day 4. ***P < 0.001. Error bars indicate mean ± SD.