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(Upper) Optimal ET pathway (red) from cytochrome c to CuA in the πu state, and (Lower) from CuA in the σu* state to the ba3 group of the oxidase. Rendered from the structure of T. thermophilus ba3 oxidase (PDB ID code 1XME) (41) and the model complex between the CuA domain and cytochrome c552 (PDB ID code 2FWL) (13).
