Fig. 2.

CSC particles derived from cell suspensions. (A) Schematic representing the formation of CSC particles. Following silicification as for adherent cells, dehydration results in a dry powder comprised of monodisperse CSC particles (B; Right shows a closeup SEM of a 4T1-templated CSC displaying a ruffled external surface). (C) Close-up SEMs of CSC particles derived from a variety of tissues. Insets show the whole particle. (D) Calcined CSCs templated from human erythrocytes showing normal to increasingly abnormal/crenate morphology resulting from increasing levels of osmotic stress (Left to Right). (E) Calcined CSCs derived from RBL-2H3 cells before (Left) and after (Right) IgE cross-linking. (Scale bars, C–E: 1 μm.)