Table 3.
Viral titers in NS and BALF samples collected at the indicated times
| Vaccine | Challenge virus | Mean viral titer ± SEM (log10 TCID50/ml)a |
|||
|---|---|---|---|---|---|
| NS at 1 dpi | NS at 3 dpi | NS at 5 dpi | BALF at 5 dpi | ||
| Ad5-empty | NC | 0.0 ± 0.0a | 0.0 ± 0.0a | 0.0 ± 0.0a | 0.0 ± 0.0a |
| Ad5-empty | CA09 | 2.1 ± 0.5b | 2.6 ± 0.3b | 2.7 ± 0.2bc | 4.9 ± 0.2b |
| Ad5-HA | CA09 | 0.0 ± 0.0a | 0.0 ± 0.0a | 0.0 ± 0.0a | 0.0 ± 0.0a |
| Ad5-empty | MN08 | 3.3 ± 0.4b | 3.4 ± 0.2c | 3.3 ± 0.3c | 4.7 ± 0.3b |
| Ad5-HA | MN08 | 3.2 ± 0.4b | 3.2 ± 0.3c | 1.0 ± 0.5a | 0.0 ± 0.0a |
| kaCA | MN08 | 2.8 ± 0.6b | 4.1 ± 0.2d | 1.9 ± 0.5b | 1.1 ± 0.8a |
a
Different letters indicate a significant difference (P < 0.05) between treatments within the time point for specific samples (NS or BALF).