Table 2.
Incidence of clinical signs post challenge
| Clinical sign | No. of animals with clinical signs/no. of animals per group (%)c |
||
|---|---|---|---|
| Treated (group 1) | Untreated (group 2) | Unchallenged (group 3) | |
| Lethargy | 9/12 (75) | 12/12 (100)* | 2/6 (33) |
| Stool abnormalitiesa | 7/12 (58) | 7/12 (58) | 3/6 (50) |
| Inappetence | 12/12 (100) | 11/12 (92) | 6/6 (100) |
| Hunched posture | 12/12 (100) | 12/12 (100) | 5/6 (83) |
| Vomiting | 5/12 (42) | 2/12 (17) | 0/6 (0) |
| Respiratory abnormalitiesb | 2/12 (17) | 7/12 (58)* | 0/6 (0) |
| Moribund | 1/12 (8) | 1/12 (8) | 0/6 (0) |
a
Stool abnormalities included soft stool, no stool, diarrhea, or mucous stool.
b
Respiratory abnormalities included respiratory distress, labored respirations, wheezing, or coughing.
c
*, P < 0.05 compared to the unchallenged (group 3).