Table 1.
Geometric mean Fim2-Fim3, Fim2, and Fim3 ELISA IgG concentrations in vaccineesa
| Age group | Geometric mean IgG ELISA concn units (95% CI) |
Fim2/Fim3 ratio (95% CI) | |||||
|---|---|---|---|---|---|---|---|
| Fim2 + Fim3 |
Fim2 |
Fim3 |
|||||
| Pre | Post | Pre | Post | Pre | Post | ||
| 15 mo old, after 4th dose of aP5 (n = 15) | 21 (16, 29) | 634 (459, 875) | 20 (13, 31) | 695 (504, 958) | 7 (4, 13) | 206 (126, 335) | 3.4 (2.0, 5.6) |
| 4–6 yr old, after 5th dose of aP5 (n = 15) | 26 (17, 40) | 871 (661, 1,145) | 23 (15, 37) | 801 (464, 1,383) | 6 (3, 11) | 230 (111, 475) | 3.5 (1.5, 8.2) |
| 11–18 yr old, after adolescent dose of aP5 (n = 15) | 18 (11, 29) | 2027 (1,502, 2,735) | 14 (10, 20) | 1,509 (828, 2,751) | 8 (4, 16) | 980 (571, 1,683) | 1.5 (0.6, 3.9) |
a
Pre and post, before and after vaccination, respectively; aP5, 5-component acellular pertussis vaccine.