Table 2.
Sensitivity and specificity for different Liaison IgG cutoff values for differentiation in noninfected and congenitally infected children at 6, 9, and 12 months of life
| Time point (mo of life) for analysis of peripheral blood samples | Cutoff value used (IU/ml) | Sensitivity (%) | 95% CI | Specificity (%) | 95% CI |
|---|---|---|---|---|---|
| 6a | >4.5 | 97.6 | 91.6–99.6 | 23.3 | 17.2–30.3 |
| >8.8d | 96.4 | 89.9–99.2 | 37.8 | 30.5–45.5 | |
| 9d | >5.6 | 94.6 | 84.9–98.8 | 78.4 | 68.8–86.1 |
| >8.8d | 87.3 | 75.5–94.7 | 87.6 | 79.4–93.4 | |
| 12c | >5.0 | 79.4 | 67.9–88.3 | 96.7 | 90.7–99.3 |
| >8.8d | 75.0 | 63.0–84.7 | 96.7 | 90.7–99.3 |
a
NI group, n = 172; CT group, n = 84.
b
NI group, n = 97; CT group, n = 55.
c
NI group, n = 91; CT group, n = 68.
d
According to the manufacturer's recommendation.