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Sunitinib levels in mouse plasma and xenograft tumor specimens. Sunitinib concentrations were examined as indicated in Materials and Methods section.
| Mean sunitinib concentrations | ||
|---|---|---|
| Plasma | Tumor | |
| Experimental group #1 (n = 3) | 4.63 μM | 54 μM |
| Experimental group #2 (n = 3) | 4.63 μM | 48 μM |
| Experimental group #3 (n = 3) | 7.08 μM | 98 μM |
| Mean (SEM) | 5.4 (0.8) | 66.7 (15.8) |
