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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Kidney Int. 2011 Aug 10;80(11):1198–1211. doi: 10.1038/ki.2011.261

Figure 5. Time course of serum cytokines (HMGB1, VEGF, TNF-α, IL-6 and IL-10) following CLP with or without pre-existing kidney impairment.

Figure 5

Serum HMGB1 (A), VEGF (B), TNF-α (C), IL-6 (D) and IL-10 (E) at indicated time points in CD-1 mice after normal-CLP, 5/6 Nx-CLP or bilateral Nx-CLP. (n = 4–5/time point). By repeated measures ANOVA all except IL-6 had significant time x nephrectomy interactions; post-hoc (Tukey) comparisons: * P<0.05 vs. normal-CLP, # P<0.05 vs. 5/6 Nx-CLP.