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. 2012 Nov 7;103(9):1870–1879. doi: 10.1016/j.bpj.2012.09.018

Figure 1.

Figure 1

Effect of the ceramide analogs on the order of POPC bilayers. The mean fluorescence lifetimes of tPA (0.5 mol %) were measured in multilamellar vesicles composed of POPC or POPC/Cer (85/15 mol %, 100 μM final lipid concentration) at 23°C. The mean lifetime of tPA in the presence of 12:1- and 14:1-PCer was close to that of pure POPC, whereas 16:1-, 18:1-, and 20:1-PCer induced a chain-length-dependent increase in the mean lifetime. The average intensity-weighted lifetimes ± SD for triplicates are shown.