Figure 1.

Peak viremia was 100-fold lower in PrEP/ARV-treated macaques relative to control macaques (P = .02, Wilcoxon rank-sum test). Plasma viral load was measured by quantitative reverse-transcriptase polymerase chain reaction. The detection limit was 50 copies/mL (dotted line). Shown are mean values and standard error of the mean (SEM) for control (grey) and PrEP-treated animals (black). Temporal decrease in virus load (log-10) after peak viremia differed between PrEP/ARV-treated macaques relative to control macaques (mixed effects regression analysis, P = .04).