Table 1.

STAIR quality of APC using Experimental Stroke Scale Modified by O’Collins et al. (ref. 13)

*STAIR criterion	Description	Score	Refs
Laboratory setting	Focal model tested in two or more laboratories	YES	42,49,75,76
Animal species	Focal model tested in two or more species	YES	49,75,76
Health of animals	Focal model tested in old or diseased animals	NO
Sex of animals	Focal model tested in male and female animals	YES	49,54,62
Reperfusion	Tested in temporary and permanent models of focal ischemia	YES	42,43,49,54,75
Time window	Drug administered at least 1 hour after occlusion in focal model	YES	42,43,64
Dose response	Drug administered using at least two doses in focal model	YES	49,54
Route of delivery	Tested using a feasible mode of delivery (eg, not intracisternal or intraventricular, cortical transplant or graft only)	YES	42,43,54,64,75
Endpoint	Both behavioral and histological outcome measured	YES	42,43,54,64,65
Long-term effect	Outcome measured at 4 weeks after occlusion in focal models	NO

^*STAIR criteria are not given in order of priority