Table 1.
Patient Characteristics
| Characteristic | PCV7 (N = 91) | PPSV23 (N = 90) | P value |
|---|---|---|---|
| Age, years | 63 ± 9 | 64 ± 10 | .56 |
| Male, n, (%) | 59 (65) | 52 (58) | .36 |
| Caucasian, (%) | 70 (77) | 71 (79) | .86 |
| FEV1, (L) | 1.33 ± 0.53 | 1.27 ± 0.50 | .37 |
| FEV1, (% predicted) | 44.9 ± 15 | 44.8 ± 15 | .96 |
| FVC | 2.91 ± 0.85 | 2.86 ± 1.0 | .73 |
| FEV1/FVC | 0.46 ± 0.13 | 0.45 ± 0.12 | .66 |
| Oxygen use, n (%) | 21 (23) | 29 (32) | .19 |
| Inhaled corticosteroid use, n (%) | 60 (66) | 58 (64) | .88 |
| Pack-Years smoking | 52 ± 28 | 55 ± 27 | .48 |
| Current Smoker, n (%) | 33 (36) | 32 (36) | 1.0 |
| Co-Morbid Illness, n (%) | |||
| Coronary Artery Disease | 22 (24) | 19 (21) | .72 |
| Congestive Heart Failure | 3 (3) | 5 (6) | .50 |
| Stroke | 3 (3) | 7 (8) | .21 |
| Diabetes Mellitus | 8 (9) | 7 (8) | 1.0 |
| Prior Malignancy | 9 (10) | 12 (13) | .50 |
| Anemia | 12 (13) | 5 (6) | .12 |
| Previous Pneumonia, n (%) | 44 (48) | 45 (50) | .88 |
| Exacerbation History (Year Prior to Enrollment) | |||
| Hospitalized or unscheduled emergency visit, n (%) | 18 (20) | 11 (12) | .22 |
| Number of hospitalizations or unscheduled ED visits in past year for those with any. | 1.2 ± 0.9 | 1.2 ± 0.6 | .90 |
| Received systemic steroids and/or antibiotics, n (%) | 38 (42) | 34 (38) | .65 |
| Number of courses of systemic steroids and/or antibiotics in past year for those with any courses. | 1.9 ± 1.6 | 1.6 ± 1.0 | .28 |
| Vaccine naive, n (%) | 45 (49) | 42 (47) | .77 |
| Years since last vaccination | 7.6 ± 2.7 | 8.4 ± 3.5 | .19 |
Results are mean ± standard deviation, unless indicated.
Abbreviations: ED, emergency department; FEV1, forced expiratory volume; FVC, forced vital capacity; L, liters; PCV7, 7-valent diphtheria-conjugated pneumococcal polysaccharide vaccine; PPSV23, 23-valent pneumococcal polysaccharide vaccine.