Table 2.
SNP ID | Nearest gene | Coded allele | Minor allele frequency | Directionality of the GFR related to the coded allele | Odds ratio related to the coded allele (95% confidence interval) | P-value* |
---|---|---|---|---|---|---|
rs17319721 | SHROOM3 | A | 0.43 | – | 0.88 (0.83–0.93) | 1.87E-06 |
rs11959928 | DAB2 | A | 0.44 | – | 0.97 (0.92–1.02) | 0.26 |
rs1394125 | UBE2Q2 | A | 0.35 | – | 0.95 (0.90–1.01) | 0.13 |
rs10109414 | STC1 | T | 0.42 | – | 0.95 (0.91–1.00) | 0.07 |
rs1260326 | GCKR | T | 0.41 | + | 1.07 (1.01–1.12) | 0.02 |
rs267734 | ANXA9 | C | 0.2 | + | 1.03 (0.97–1.10) | 0.36 |
rs7805747 | PRKAG2 | A | 0.24 | – | 1.07 (0.98–1.16) | 0.15 |
rs4744712 | PIP5K1B | A | 0.39 | – | 0.96 (0.91–1.01) | 0.11 |
rs6420094 | SLC34A1 | G | 0.34 | – | 1.01 (0.94–1.08) | 0.84 |
rs626277 | DACH1 | C | 0.4 | + | 1.00 (0.95–1.06) | 0.93 |
rs12460876 | SLC7A9 | C | 0.39 | + | 0.97 (0.92–1.03) | 0.30 |
rs653178 | ATXN2 | C | 0.5 | – | 1.00 (0.94–1.05) | 0.88 |
rs881858 | VEGFA | G | 0.28 | + | 1.00 (0.94–1.06) | 0.95 |
rs13538 | ALMS1 | G | 0.23 | + | 1.08 (1.02–1.16) | 0.01 |
rs12917707 | UMOD | T | 0.18 | + | 1.03 (0.96–1.10) | 0.46 |
rs347685 | TFDP2 | C | 0.28 | + | 1.01 (0.95–1.07) | 0.74 |
Statistical significance defined using a Bonferroni correction for the 16 SNPs (0.05/16 = 0.003).