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. 2012 Jun 25;120(10):1378–1384. doi: 10.1289/ehp.1104406

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Penalized regression spline of exposure to PM₁₀ (A), O₃ (B), and NO₂ (C) on lag day 4, lag day 5, and lag day 7, respectively, on glucose (top), insulin (center), and HOMA (bottom) indices by 0–1 (left) or 2–3 (right) risky genotypes. Solid lines, spline curve; shaded area, 95% CI. The curves are adjusted for age, sex, BMI, cotinine level, and outdoor temperature and dew point of the day.